Papers
80 papers · showing 20
Simulating 500 million years of evolution with a language model.
protein-ml · DOI 10.1126/science.ads0018 · Science · 732 citations
proteingeneration
Jan 2025
Genome modeling and design across all domains of life with Evo 2
genomics · DOI 10.1101/2025.02.18.638918 · bioRxiv (Cold Spring Harbor Laboratory) · 217 citations
dnagenomics
Feb 2025
Scupa: single-cell unified polarization assessment of immune cells using the single-cell foundation model.
single-cell · DOI 10.1093/bioinformatics/btaf090 · Bioinformatics · 1 citation
single-cell
Mar 2025
Scaling Large Language Models for Next-Generation Single-Cell Analysis
single-cell · DOI 10.1101/2025.04.14.648850 · bioRxiv (Cold Spring Harbor Laboratory) · 38 citations
single-cellllm
Apr 2025
Virtual Cell Challenge: Toward a Turing test for the virtual cell.
single-cell · DOI 10.1016/j.cell.2025.06.008 · Cell · 82 citations
single-cellperturbationbenchmark
Jun 2025
Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction
protein-ml · DOI 10.1101/2025.06.14.659707 · bioRxiv (Cold Spring Harbor Laboratory) · 601 citations
proteinstructure
Jun 2025
Predicting cellular responses to perturbation across diverse contexts with State
single-cell · DOI 10.1101/2025.06.26.661135
single-cellperturbation
Jun 2025
RiNALMo: general-purpose RNA language models can generalize well on structure prediction tasks.
rna-ml · DOI 10.1038/s41467-025-60872-5 · Nature Communications · 92 citations
rnasequence
Jul 2025
rbio1 - training scientific reasoning LLMs with biological world models as soft verifiers
single-cell · DOI 10.1101/2025.08.18.670981 · bioRxiv (Cold Spring Harbor Laboratory) · 7 citations
single-cellreasoning
Aug 2025
imAgeScore, a Cell Painting-Based Predictor of Cellular Age for High-throughput Drug Screening Applications
cell-imaging · DOI 10.64898/2026.03.06.710056 · bioRxiv (Cold Spring Harbor Laboratory) · 0 citations
imaging
Mar 2026
Machine learning for RNA secondary structure prediction: a review of current methods and challenges.
rna-ml · DOI 10.1261/rna.080840.125 · RNA · 2 citations
rna
Mar 2026
Illuminating cell states by a comprehensive and interpretable single cell foundation model.
single-cell · DOI 10.1038/s41467-026-70071-5 · Nature Communications · 2 citations
single-cell
Mar 2026
Progress and new challenges in image-based profiling.
cell-imaging · DOI 10.1038/s44320-026-00197-7 · Molecular Systems Biology · 4 citations
imaging
Mar 2026
Crosstalk between RNA secondary and three-dimensional structure prediction: a comprehensive study.
rna-ml · DOI 10.1080/15476286.2026.2655096 · RNA Biology · 0 citations
rna
Apr 2026
Pre-training genomic language model with variants for better modeling functional genomics.
genomics · DOI 10.1038/s44387-026-00103-4 · npj Artificial Intelligence · 3 citations
dnagenomics
Apr 2026
Automated Morphological Profiling via Deep Learning-Based Segmentation for High-Throughput Phenotypic Screening.
cell-imaging · DOI 10.3390/jimaging12040179 · Journal of Imaging · 0 citations
imaging
Apr 2026
ITCNET: a visual and language pretraining model based on multimodal fusion in predicting the breast cancer subtypes on DCE-MRI.
medical-imaging · DOI 10.1186/s12911-026-03513-1 · BMC Medical Informatics and Decision Making · 0 citations
imaging
Apr 2026
Evolving computational paradigms for noncoding variant pathogenicity prediction.
genomics · DOI 10.3389/fmolb.2026.1761673 · Frontiers in Molecular Biosciences · 0 citations
dnagenomics
Apr 2026