protein-ml/proteingym-v1

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benchmarkbiologydeep-learningdmsproteinprotein-fitness
Visibility: PUBLIC Updated 9/10/2026
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Overview

ProteinGym is a benchmark suite for evaluating protein fitness prediction and design models. It includes both substitution and indel mutations, a wide variety of experimentally assayed proteins, and clinically annotated mutations that are relevant to human disease. In total, ProteinGym includes nearly 3 million different