Perturbation DE-gene overlap from predicted cells (Norman CRISPRa)

single-cell

single-cell/perturbation-response-delta-pearson-sampled-cells Task: regression Visibility: PUBLIC

Overview

The Norman 2019 K562 CRISPRa benchmark (GEARS simulation split, 107 held-out perturbations) scored the way cell-eval scores perturbation models: the model returns predicted single cells, a Wilcoxon test against the control cells finds their differentially expressed genes, and the top 20 are compared with each perturbation's measured top-20 DE genes.

Leaderboard

Ranked results, with their source, uncertainty and floors, the protocol and a sample of the data are on the Leaderboard tab.